Crescentic glomerulonephritis developing in the course of idiopathic membranoproliferative glomerulonephritis

Chapter 8: Idiopathic membranoproliferative glomerulonephritis

BACKGROUND MPGN is a light-microscopic ‘‘pattern of injury’’ caused by many disorders (see Table 20). Patients commonly present with nephrotic syndrome, hypertension, glomerular hematuria, and progressive kidney dysfunction. Reduction in the serum concentration of complement components (C3 and/or C4) is commonly, but not uniformly, observed. MPGN can be further classified based on the extent an...

Membranoproliferative Glomerulonephritis

Membranoproliferative glomerulonephritis (MPGN) refers to glomerular pathology in which there is thickening of the capillary wall together with mesangial expansion. In this article we firstly review the pathological features of MPGN and discuss how advances in our understanding of the association between abnormalities in the regulation of complement and MPGN have revealed limitations in the his...

Membranoproliferative glomerulonephritis.

Glomerulonephritis (GN) encompasses a wide variety of primary and secondary diseases that cause injury to the functioning unit of the kidney, the glomerulus. The many classifications of GN sometimes lead to confusion. This case study describes an individual with membranoproliferative GN and includes discussion of classification, treatment, and prognosis of this disease.

Acute crescentic glomerulonephritis developing during warfarin therapy.

Retinal findings in membranoproliferative glomerulonephritis

Purpose To assess the evolution of retinal findings in patients with membranoproliferative glomerulonephritis (MPGN) by funduscopy, intravenous fluorescein angiography and optical coherence tomography. Observations Three women and one man were followed for a period of 1.5-37 years. Four patients (8 eyes) had drusen detected at first fundus exam at age 24, 29, 50 and 55. Three patients (6 eyes...